Zuma said the ANC was projected by the opposition in that as no longer enjoying majority support.
"The ANC is supported by the overwhelming majority", he said, before breaking boisterously into song, cracking jokes and telling his supporters that the opposition had been thwarted in an attempted power grab.
The leader of the opposition Democratic Alliance had urged the lawmakers to oust President Jacob Zuma at the start of the parliamentary debate, but the ANC lawmakers ignored the calls and backed the President.
"Let's uphold the will of the people", said DA leader Mmusi Maimane when he announced on Wednesday morning that the DA will table a motion for the dissolution of Parliament on Thursday. As the result was read, the ANC's celebrations were punctuated with shouts of "sell-out" and "traitor" across the benches to the 20 or so ANC members who likely voted against Zuma.
Hundreds of anti-Zuma protesters who gathered outside Parliament, anxiously waiting for the result, expressed disappointment over the outcome.
Mr Zuma, in power since 2009, has struggled to fend off accusations of corruption and mismanaging the economy. There will be a stamp on the ballot paper to verify it. MPs will make their vote and put their papers into a box while party chief whips monitor the voting to ensure irregularities are avoided.
"Overall, though, around 60-70 ANC MPs (out of a total of 249 ANC MPs) would probably need to rebel for the motion to pass", Jackson said in a note.
If Zuma had lost, he would have been forced to resign along with his entire cabinet.
Baleka Mbete, the country's parliament speaker, made the decision to hold the vote in secret on Monday after opposition parties took the case to the Constitutional Court.
Disgruntlement with Zuma's leadership contributed to the party's worst-ever electoral performance in a municipal vote in August previous year and several of its senior leaders have warned that it's in danger of losing its overall majority in 2019 elections.
"It's time for a new beginning that will bring total change in South Africa".
Opposition parties and the Future South Africa coalition of social, religious and community organisations have vowed to intensify their battle to get Zuma recalled by the ANC.
While Zuma's term continues until elections in 2019, there have been calls from within the ANC for him to quit earlier and allow the party to build up support before the vote.