"And when that day finally dawns it will be because of a lot many magnificent women. and some pretty phenomenal men fighting hard to make sure that they become the leaders who take us to the time when nobody ever has to say "Me too" again".
The theme was echoed by Laura Dern, victor of a best supporting actress for Big Little Lies, who said: "Many of us were taught not to tattle".
McDormand - who was nominated in years past for such films as Fargo, Almost Famous, and Burn After Reading (and also received a special award in 1994 as part of the cast of Short Cuts) - plays a mother waging a war against local authorities when police fail to solve her daughter's murder.
The glittering 75th Golden Globes ceremony, honouring achievements in television and cinema, sent out the message that a new post Harvey Weinstein-era could be on the horizon. On the comedy side of things, Lady Bird won Best Motion Picture Musical or Comedy and the film's star Saoirse Ronan picked up her first win for Best Actress in a Motion Picture Musical or Comedy.
Lady Bird's win for Best Musical or Comedy was announced first.
Women kept up the theme inside the Beverly Hilton ballroom.
While it was a big night for streaming video companies, HBO - which has its own, popular subscription-based streaming service - also won big at the ceremony.
Today, arts and entertainment writers John Semley and Tina Hassannia are in the q studio to talk about the surprises, the snubs, and the speeches that made an impression at this year's Golden Globe Awards.
Women in the industry have launched the Time's Up movement to address gender disparity and abuse and nearly all of Hollywood - both women and men - turned up in black at the red carpet to show their support.
-Series, Drama - "The Handmaid's Tale".
Laura Dern, a supporting actress victor for "Big Little Lies", said: "May we teach our children that speaking out without retribution is our culture's new north star".
Based on the novel by André Aciman, Call Me By Your Name tells the story of Elio (Timothée Chalamet) who falls in love with Oliver, (Armie Hammer), an American academic who comes to stay at his family's home in Italy during the summer of 1983.