James Brokenshire has resigned as Northern Ireland secretary due to ill health, as the rest of the cabinet stands ready to learn their fate in Theresa May's reshuffle.
The reshuffle - the biggest of Mrs May's tenure - was prompted by the resignation of Damian Green after he admitted lying over pornography on his office computer.
Departures from the Cabinet included Northern Ireland Secretary James Brokenshire, replaced by outgoing Culture Secretary Karen Bradley.
David Lidington replaces Damian Green as Minister for the Cabinet Office but is not made First Secretary of State.
The Prime Minister offered Greening a job at the Department for Work and Pensions but failed in her attempt to keep the minister from quitting in protest at the move from education.
Ms Rudd is taking over the role of Minister for Women and Equalities previously held by Ms Greening, Downing Street sources said.
'Makes one wonder who's in charge.' Ms Greening appeared to confirm the reports that she had refused a move by saying: 'Social mobility matters to me and our country more than my ministerial career. With Boris Johnson, David Davis and Philip Hammond untouched, Theresa May has managed to effect a deft intra-party exercise.
McLoughlin had been widely blamed for last year's disastrous election campaign, and for the security lapse that allowed prankster Simon Brodkin into the party conference to hand the Prime Minister a fake P45 during her speech.
David Gauke leaves the DWP to become Justice Secretary, while his old job goes to Esther McVey.
The UK government's accident-prone streak continued in the new year as British Prime Minister Theresa May's weaker than expected Cabinet reshuffle began with an erroneous tweet from the Conservative Party's official Twitter account wrongly announcing the party's new chairman.
Also remaining at the top table is Michael Gove (Environment Secretary), Penny Mordaunt (International Development Secretary), Chris Grayling (Transport Secretary), Jeremy Hunt (Health Secretary) who has been given added responsibility for social care.
Andrea Leadsom, Leader of the House of Commons, has also retained her position - despite earlier rumours to the contrary.
The Times later reported that there had been "internal pushback" against Grayling, with o ther reports suggesting that the Conservatives had mistakenly announced Grayling's appointment due to it being reported by the BBC.
It was later confirmed that Brandon Lewis, formerly immigration minister, was the new party chairman. Rising star James Cleverly, who is open about his prime ministerial ambitions, is a step closer to realising those with his first promotion - he joins Cabinet as Lewis' deputy.
If this was the prime minister's goal, she failed here too, ignoring some of the party's rising stars such as Tom Tugendhat and Johnny Mercer altogether and moving others from positions where they shone to posts for which they are not obviously qualified.
Caulfield led opposition to the campaign to decriminalise abortion past year, arguing that more consideration should be given to the rights of the unborn child.