The foundation of the new office was laid by PM Modi and BJP president Amit Shah in 2016 and the construction work completed before its deadline. It was inaugurated by Modi in the presence of the party leaders.
BJP is the first party to comply with the Supreme Court's order to shift out of the Luyten's Bungalow area in Delhi.
"Jan Sangh and BJP leaders have been at the forefront of all leading mass movements post Independence".
The party's core values are steeped in democracy, he said, adding that it is guided by a democratic spirit in its thinking, working and executing its agenda.
Dedicating the new headquarters to 11 crore party workers and their dreams, Prime Minister Narendra Modi termed the building as a centre for service to the nation.
The party headquarters will be linked through videoconferencing to all the state headquarters of the party and will have a state-of-the-art library boasting of party literature and subscriptions to some of the latest journals from across the world.
The BJP chief said, "Today is a very auspicious day for the BJP".
Party president Amit Shah, Union ministers Rajnath Singh, Sushma Swaraj and senior leaders Murli Manohar Joshi and LK Advani were also present among others.
Entry to the office will be regulated initially, though its full features will be revealed eventually.
He also remembered the party workers who had dedicated their lives to the BJP.
The Congress now operates at 24 Akbar Road, also a Lutyens' bungalow.
There are three entry points in the newly constructed office.
However, the new party office for the BJP will come with its own set of problems.