Richard Shotcroft, the film producer, said: "RIP the wonderful Emma Chambers - best known for The Vicar of Dibley but also stole every scene in Notting Hill".
"Knew her when she was a kid in Doncaster".
In the movie, she plays Honey, Hugh Grant's little sister and the romantic interest of Rhys Ifans' character Spike.
She was known for playing Alice Tinker in the BBC show and for her secondary role in Notting Hill.
John Grant said in a statement: "We are very sad to announce the untimely death, from natural causes, of the acclaimed actress, Emma Chambers".
Following the news of her passing, many of her co-workers and people in the entertainment industry took to Twitter to mourn including Hugh Grant who wrote that "Emma was a hilarious" and incredibly "warm" person. Jodie Marsh took the time to express how much she loved Emma's work in Notting Hill and said the film made her cry. The long-standing series ran from 1994 to 2007. Notting Hill co-star James Dreyfus posted about how she was "unique" and "unspeakably amusing".
Emma is survived by her husband, fellow actor Ian Dunn.
She tied the knot in 1991 at a low-key ceremony in New Forest and described her marriage as "glorious" in an interview in January this year.
"The joke coda with Dawn French in Dibley required great skill and Emma just nailed it".
"My wedding was very short". "I loved working with her, she was stunning", he said, according to the outlet.
"It is one of those odd things, because when you start working on something, you think it is one thing and it becomes something quite different", he continued.