Earlier this season, Chelsea registered a 2-1 win in the East Midlands before the two teams played out a goalless draw at Stamford Bridge.
Cesar Azpilicueta has been rested in the FA Cup at times this season but we're getting towards the business end of the competition so I think the Spaniard will keep his place alongside Andreas Christensen.
"Don't forget that two years ago Chelsea finished 10th, with many players who have featured this season", said Conte.
Asked whether he was more focused on securing a top-four spot or lifting the FA Cup, Conte replied: "I think we have to try to do both".
The Italian's side were eliminated from the Champions League after a 3-0 Nou Camp defeat to Barcelona on Wednesday and the defending champions are also fifth in the Premier League, four points behind Liverpool.
"Do the players need to take responsibility?"
The defending Premier League champions are facing the real prospect of finishing the season without any silverware in Antonio Conte's second season in charge.
Mark Chapman will present the BBC One coverage from the DW Stadium as Wigan go in search of a fourth Premier League scalp having already beaten Bournemouth, West Ham and Manchester City.
"Leicester is a good team". We try to do our best in every competition.
Puel acknowledges the tie is important for his side, but he also hopes there will be bigger games to come this season for his players. In the last game we played at home, we suffered against them.
Midfield: N'Golo Kante is expected to be retained in the middle of the park but I think we could see Conte leave Cesc Fabregas out of the starting eleven on Sunday.