Headers by Romelu Lukaku and Nemanja Matic earned Manchester United an unconvincing 2-0 victory over Brighton and Hove Albion in a low-key FA Cup quarter-final played in freezing conditions on Saturday.
Jose Mourinho has made five changes from the side knocked out of the Champions League by Sevilla, with Sanchez missing out for the first time since arriving from Arsenal in January following 10 successive starts.
The Red Devils will welcome Chris Hughton's side to Old Trafford in their FA Cup last-eight clash with a place in the semi-finals at Wembley up for grabs.
The hosts finally worked a clear opening in the 29th minute as Juan Mata and Jesse Lingard rapidly swapped passes, the Spain global seeing his shot deflect wide.
Locadia was proving a handful but he should have done better with a headed chance after March beat Young and delivered a deep right-wing cross to the back post.
- Mourinho has won 15 of his 17 home FA Cup matches (D1 L1), winning all three with Manchester United by an aggregate score of 12-0.
Having failed to get a single shot away of any note between half time and the 83rd minute, United finally killed the game off when Matic watched Ashley Young's free kick all the way and guided it past Krul via his head.
It will be held at Old Trafford.