President Donald Trump said the air strikes were in response to the "evil and despicable" chemical attack on April 7 which left "mothers and fathers, infants and children, thrashing in pain and gasping for air".
Alexander Yakovenko, the Russian ambassador to London, said the White Helmets, a British-funded civil defense force, were responsible for staging fake chemical attacks.
May said the missile strike was created to minimize any civilian casualties and was not an attempt to change the Syrian government.
Let it be known that the United States, Britain and France carried out a wave of strikes against Bashar al-Assad's regime on Friday in Syrian capital, drawing the ire of Russian Federation.
The Prime Minister explained: "I have taken this decision because I believe it is the right thing to do".
Despite her careful language, there was immediate criticism from opposition lawmakers who said May should have consulted parliament before joining US-led action in Syria. Western governments, including Britain, blamed the government of Bashar al-Assad, a Russian ally, for the attack.
"It was both right and legal to take military action together with our closest allies to alleviate further humanitarian suffering by degrading the Syrian regime's chemical weapons capability", May said.
"The consequences of any country taking unilateral and action that has no legal basis are that it's an encouragement for others to do exactly the same and reduces our ability to complain when others do that", he said.
Britain's defense ministry said "very careful scientific analysis" had been applied to maximize the destruction of stockpiled chemicals while minimizing any risk of contamination to surrounding areas.
Polls in recent days have shown public wariness of military intervention in Syria, with Britain still haunted by its participation in the US-led invasion of Iraq.
Sturgeon said the suspected use of chemical weapons was "sickening", but warned that the latest action risked "dangerous escalation".
I have done so because I judge this action to be in Britain's national interest. "We can not allow the use of chemical weapons to become normalized - within Syria, on the streets of the United Kingdom, or anywhere else in our world".
"Theresa May should have sought parliamentary approval, not trailed after Donald Trump", Corbyn said.
British Prime Minister Theresa May described the strike as "limited and targeted".
"Bombing can not substitute for diplomacy", he said.