A tough choice between two of the league's top goalkeepers.
Manchester City has won only once in the last five meetings against Spurs. He has created the highest number of chances during that spell.
Vincent Kompany is, however, able to step back in at centre-half after being an unused substitute in midweek.
This season the 18-consecutive victories between August and December set a new Premier League record and the has spent a total of 240 days at the summit of the league since the start of the season.
He will be desperate to help his side return to winning ways on Saturday.
Toby Alderweireld is still missing...
He also has the ability to pick out a pivotal pass. The absence of Heung-Min Son definitely made it easier as he may be Tottenham's most risky wide attacker at the moment and this may have played a role in why Pep felt comfortable doing this.
Fernandinho would come close to making up the midfield, however the defensive midfielder is suspended for the encounter. A defeat might have prompted a serious challenge from Jose Mourinho's men, but goals from David Silva and Nicolas Otamendi secured a deserved 2-1 win after the visitors controlled the majority of the action. A dutiful cog in the machine during the opening weeks, the Belgium midfielder kicked into gear and City's season duly took flight.
He has provided 11 assists and scored eight goals in the league this campaign. Pep's wait for a Champions League final appearance has been prolonged by another year, with the Spaniard last managing in a European Final in 2011. But his play as a whole has been a joy to watch.
He has the ability to produce a moment of magic like he did against Chelsea on Easter Sunday.
Tottenham's second goal in the 2-1 win at Stoke was initially given to Christian Eriksen but after the club lodged an appeal, it was given to Kane.
He has been so impressive for City that he is likely to be one of England's key men at the World Cup in June. "You could see the difference in the attitude to players compared to last week", said the Portuguese coach.
His pace and skill puts defenders on the back foot and he has a thunderous strike at his disposal. That shows their growth and how their manager's methods are working just fine as they continue working to establish their dominance over the rest of the Premier League.
Sergio Aguero could be a big miss for City as they are one of his favoured opponent.