Haris Sohail, who retains his place after he made his debut in the home series loss against Sri Lanka previous year, may also find himself in a crucial all-around role with his part-time spin.
It appears that the chief selector Inzamam ul Haq preferred his nephew Imam ul Haq over him in the test squad.
However, he was ignored while a number of younger batsmen including Saad Ali, Imamul Haq and Usman Salahuddin made the cut.
Despite it being one of his worse seasons in the domestic circuit, Fawad was the sixth highest run-scorer of the tournament with 570 runs at an average just above 40. Attempting to make up for his absence will be Shadab Khan, who has played a solitary Test, against the Windies past year.
With spinner Yasir Shah sidelined by a hip problem, fellow slow bowler Shadab Khan - a regular for his country in their limited-overs sides - could get the chance to add to his solitary Test cap.
"Yasir's absence is a big loss for us", Inzamam said.
Mohammad Amir will lead a relatively inexperienced pace attack, which includes Hasan Ali, Mohammad Abbas and Rahat Ali.
Sarfraz Ahmed, the captain, is the only specialist wicketkeeper in the squad. Pakistan then travel to England for a two-Test series beginning on 24 May at Lord's. "If we look at his numbers (of wickets) for the last two years, he has more wickets than any other bowler for Pakistan". Other than Shadab, he is the only player in the squad capable of providing a spin option of any potence, and may find himself being turned to if Pakistan are to avoid overburdening Shadab. "He played a big part in all the games we won".
Pakistan start their tour with a four-day warm-up game against Kent before playing a historic one-off Test against Ireland.