She added that she is in Georgia because of all the men and women throughout history who were "suppressed, repressed and oppressed for the right and the equality at the polls".
Abrams is running neck and neck with Georgia's Republican Secretary of State Brian Kemp.
The president was asked about Oprah Winfrey campaigning in Georgia.
"I am here today because Stacey Abrams cares about the things that matter", she said to a mostly female audience north of downtown Atlanta. But Kemp's campaign said President Trump's schedule takes precedence.
Winfrey - who sparked speculation about her own political future earlier this year - also said she wasn't considering a run for political office.
"I'd like to remind Stacey and Oprah and Will Ferrell, I'm kind of a big deal, too", Pence said, in an apparent reference to a line from Ferrell's hit 2004 film, "Anchorman".
She shared, "Georgia you've been on my mind and here's why".
"And Georgia wants a governor that's going to put Georgia values and Georgia first", he said.
On "The Five", Jesse Watters said Winfrey is an incredible and charismatic speaker, and he believes her endorsement will push Abrams across the finish line.
Kemp - who, as Georgia secretary of state, is also in charge of elections and voter registration - faced backlash after it was reported his office had put more than 53,000 voter applications on hold, almost 70% of which are from African-Americans, because they failed to clear the state's controversial "exact match" standard. I've earned the right to think for myself.
Former President Barack Obama will campaign for Abrams tomorrow. I don't want to run, ' she told the crowd.
"And I've got a message for all of Stacey Abrams' liberal Hollywood friends: This ain't Hollywood".
The Georgia gubernatorial race is one of the more contentious races of the midterm elections.
More than 1.5 million Georgians already have cast ballots.
Winfrey and Abrams greet a crowd gathered for a town hall conversation in Marietta, Ga.