In contrast, India have won 11 of their last 14 T20Is inside the last years, and with the in-form Rohit Sharma leading a strong squad, pundits have understandably held out little hope for the Windies. Several new faces have been inducted into the Indian team to test the struggling West Indies team in 3-match T20I series.
With Kohli rested for the three matches, Rohit Sharma will lead the side against the reigning T20 champions. Rishabh Pant will don the gloves in place of MS Dhoni.
West Indies chief selector Courtney Browne confirmed Russell's unavailability for the India series but did not give the details of his injury.
He has a world record score of 264 in ODIs at the Eden Gardens in 2014, besides winning two IPL titles, in 2013 and 2015.
Dhoni has been left out of India's T20 squad for the home series against West Indies and, more significantly, India's tour of Australia. The seasoned Mumbai batsman was the second highest scorer behind Kohli, scoring 389 runs at 129.66, that included two hundreds.
Andre Russell will miss Windies' T20I series against India due to injury.
In 2018, Dhoni, who has also captained India to 50-over World Cup glory in 2011, managed only 245 runs at 27.22 in 17 matches.
The Indian team has been on a roll at home for quite some time and against a weakened Windies have looked invincible for most parts of the series.
Pant is expected to fulfil the wicket-keeping responsibilities while Karthik could take on one of the positions in the outfield.
As per the latest ICC rankings, India, however, are way ahead of the Windies.
Rohit Sharma (c), Shikhar Dhawan, Lokesh Rahul, Rishabh Pant, Manish Pandey, Dinesh Karthik (wk), Krunal Pandya, Kuldeep Yadav, Jasprit Bumrah, K Khaleel Ahmed, Umesh Yadav.
It means West Indies start the series with an inexperienced side, comprising five debutants, while fast bowler Keemo Paul and batsmen Shai Hope, Shimron Hetmyer and Nicholas Pooran have played only 15 matches among them.