In the latest case Manafort was sentenced for conspiracy against the United States, which included a range of conduct from money laundering to unregistered lobbying, and a second count related to witness tampering.
Appearing in a wheelchair and in a dark suit, his hair gray, Manafort addressed the court before his sentencing, telling the judge that he had time to reflect as he was in solitary confinement and that "my behavior in the future will be very different".
But the federal judge had a harsh response to his request for leniency. Andrew Weissman, one of the prosecutors, said that Manafort may have lied because he did not want "negative consequences in terms of the other motive that Mr. Manafort could have, which is to at least augment his chances for a pardon".
Ms Jackson said at the outset of the sentencing hearing that she would not be influenced by last Thursday's sentence imposed by US District Judge T S Ellis in Alexandria, Virginia, where Manafort was convicted in August 2018 by a jury for bank fraud, tax fraud and failing to disclose foreign bank accounts. The state charges appear at least partly created to guard against the possibility that he could be pardoned by President Donald Trump and freed early on his federal convictions.
The sentencing hearings for Manafort mark a bookend of sorts for Mueller's investigation as it inches toward a conclusion.
Manafort pleaded guilty in an agreement with Mueller's team to fully cooperate with the Russian Federation probe, but Jackson ruled he violated the terms of the plea deal by lying to investigators.
He would serve more than seven years in prison in those cases.
"It is hard to overstate the number of lies and the amount of fraud and the extraordinary amount of money involved" in the federal conspiracy charges related to his foreign lobbying work and witness tampering.
Manafort pleaded guilty September 14 in the Washington case to a wide-ranging conspiracy involving obstruction of justice, money laundering, secret overseas bank accounts and false statements to the Justice Department. Even so, receiving another ten years in addition to Ellis' sentence of nearly four years could keep Manafort in prison until he is about 83.
Though Trump said late past year that he hadn't discussed a potential pardon for Manafort, he also acknowledged that the possibility wasn't "off the table".
The new charges were announced by Manhattan District Attorney Cyrus Vance just minutes after U.S. District Court Judge Amy Berman Jackson, of the District of Columbia, sentenced Manafort as part of Special Counsel Robert Mueller's investigation, leaving him with 81 months to serve behind bars as part of that case.
The jury was unable to reach a verdict on 10 counts, including conspiracy to commit bank fraud and bank fraud. "He engaged in crime again and again, he has not learned a harsh lesson". He agreed to cooperate with the investigation and has yet to be sentenced.
The new charges from NY are significant because Trump can't pardon him for crimes at the state level, guaranteeing that Manafort will serve at least some prison time.
Jackson indicated she thought Manafort's plea was an appeal to President Donald Trump for a pardon, something the president has not ruled out.
Manafort has not yet entered a plea in the Manhattan case.
The Mueller team had prosecuted Manafort in Washington and Virginia for his foreign consulting work on behalf of a pro-Russia Ukrainian political party.